What's the difference between Collagen Protein and Whey Protein?

By Chief Nutrition

What's the difference between Collagen Protein and Whey Protein?

While whey protein concentrate has long been the go-to option for muscle growth and recovery, collagen protein supplements have surged in popularity thanks to their unique benefits for connective tissue, joints, skin, and gut health. Both proteins are valuable but serve different purposes in the body. 

Let's look at both individually and then compare.


What is Whey Protein?

Whey protein is derived from milk and is considered a complete protein, meaning it contains all nine essential amino acids your body can’t produce on its own. It’s particularly rich in leucine, the amino acid most strongly linked with muscle protein synthesis. That makes whey especially effective for building and maintaining lean muscle mass.

Whey protein concentrate (WPC) is less processed than whey isolate (WPI), meaning it retains small amounts of fat, lactose, and other beneficial compounds found in dairy. It’s highly digestible, absorbed quickly, and has one of the highest biological values of any protein source. This is why athletes often choose whey after workouts, because it helps repair muscle fibres, supports strength gains, and helps recovery.

Beyond the gym, whey also contributes to overall health. Research suggests it may help with appetite control, support immune function through bioactive peptides, and improve metabolic health. In short: whey is the classic all-rounder protein powder, known for its role in muscle building but offering wider benefits too.


What is Collagen Protein?

Collagen is the most abundant protein in the body, making up a huge part of your skin, hair, nails, joints, tendons, ligaments, cartilage, and even gut lining. Unlike whey, collagen is not a complete protein, it’s missing tryptophan, one of the nine essential amino acids.

But that doesn’t mean it’s less important. Collagen has a completely different amino acid profile, high in glycine, proline, and hydroxyproline. These are building blocks you don’t get much of from whey or most other common proteins. These amino acids are crucial for the repair and maintenance of connective tissues.

Studies show that supplementing with hydrolysed collagen peptides can:

  • Support joint health and reduce exercise-related joint pain.

  • Improve skin hydration, elasticity, and thickness, reducing fine lines and wrinkles.

  • Strengthen hair and nails.

  • Aid in gut health by supporting the integrity of the intestinal lining.

  • Contribute to tendon and ligament recovery, which is essential for athletes and anyone prone to injury.

In other words, collagen isn’t about bulking up muscle, it’s about strengthening the tissues that hold everything together.

Side note: if you’re avoiding dairy and want to stick with Collagen protein only, you can still easily round out the amino acid profile with other whole foods. For example, our collagen bars contain cashews, which naturally provide tryptophan. And of course, our beef bars and biltong are complete proteins in themselves, with all the essential aminos including tryptophan. 


Collagen vs Whey: Complementary, Not Competing

The biggest difference comes down to function. Whey provides the full spectrum of essential amino acids with a focus on muscle protein synthesis. Collagen supplies amino acids that are scarce in the modern diet but critical for connective tissue repair and resilience.

Think of whey as fuel for the engine (muscle) and collagen as maintenance for the framework (tendons, joints, skin, and gut). Both are useful on their own, but together they create a more complete picture of health and performance.

For athletes, combining whey and collagen can be especially powerful. Whey drives muscle recovery after training, while collagen helps fortify tendons and ligaments to prevent injuries. For everyday health, whey helps maintain muscle as you age, while collagen supports skin health and mobility, two areas people often struggle with over time.

 


Which One Should You Choose?

It depends on your goals and needs:

  • If your priority is building muscle, strength, and recovery after workouts, whey protein concentrate is the gold standard. 

  • If you’re focused on gut health, joint health, skin support, or repairing connective tissues, collagen protein is the better choice. It's also a dairy free option and better tolerated by many people (note that our Vanilla Collagen contains buttermilk which is lower lactose but still dairy). 

  • If you want comprehensive benefits for both muscle and connective tissue, use both strategically.


The Bottom Line

Whey protein concentrate and collagen protein supplements aren’t rivals, they’re partners. Whey shines for muscle growth and overall protein needs, while collagen delivers specialised amino acids that nourish tissues often overlooked. When combined, they offer a more holistic approach to health, performance, and longevity.

Whether you’re an athlete chasing strength gains, or simply looking to stay active, pain-free, and youthful as you age, collagen and whey together can be a winning formula.

4 comments

  • Arwen on

    Hi there! Really interesting information! I’ve been taking your Collagen protein powder for a few months now and it is the only protein powder that I tolerate well (and I don’t get sick of the taste). But reading about the benefits of whey protein made me think that it could be good for me to combine the two. How would you recommend to do that? Have them together? Or is that too much protein powder at once? What is the maximum amount of protein powder someone should have in a day? (I lift heavy weights 3-4 times/week and I’m on a high protein diet). Thanks so much!
    ———
    Chief Nutrition replied:
    For the best performance outcomes, take 15g of collagen 30-60min before training and 30g of whey after training. There’s no maximum amount of protein one can have; however, for someone who lifts heavy weights, we would recommend 1.5-2 g of protein per kg of body weight per day.

  • Raymond on

    Great article!
    Covers a lot of the useful information that Huberman Lab has covered but much more concisely. Good points about the essential amino acids and especially leucine.

    I would be curious about any comments or articles you have about Casein protein or which protein may be better for keto diet / fasting. Maybe some general dietary ideas – like when should you use protein powder in addition to a whole food diet – with meals or seperately, from my understanding the timing of when you take it doesn’t matter so much (exception seems to be BCAAs and electrolytes) so I guess with meals is fine.
    Technically eating protein does break a fast, but I am curious to learn about these things. For example, how does taking casein in the morning influence fasting etc.
    ———
    Chief Nutrition replied:
    Thanks Raymond!

    Re casein vs whey: Casein digests much more slowly than whey, so it gives a steady release of amino acids over hours. That’s why some people like it before bed, or if they’re going long stretches between meals. Whey, on the other hand, is rapid and spikes muscle protein synthesis more strongly. Both can be useful depending on context.

    Re keto / fasting: As you mentioned, all protein powders (whey, collagen, casein) will technically break a fast, but can still work within a time-restricted eating window. For keto, it’s more about choosing proteins without added carbs, so unflavoured whey or collagen work well.

    Re timing: For most people, total protein across the day is what matters most. Timing is less critical unless you’re training hard, in which case protein within a couple of hours of exercise can support recovery. It’s totally fine to combine any protein with meals and it may even improve satiety.

    We’ll try to do some deeper dives into the above.
    ———
    Chief Nutrition replied:
    These are all great questions. We will keep them in mind for our next blogs. Generally speaking, anything that contains calories will break a fast. Unless you are after muscle hypertrophy specifically, it doesn’t really matter when you consume protein, as long as you cover your daily requirement. However, the muscle protein synthesis seems to be the highest before 10 am and after hypertrophy training. A ketogenic diet is high in fat and moderate in protein. Consuming too much protein and not enough fat can kick you out of ketosis, so definitely add fats to your protein supplements.

  • Gillian Chesterfield on

    Super interesting. Would you consider adding tryptophan to your collagen powder to round out the aminos? For those of us that can’t tolerate dairy?
    ———
    Chief Nutrition replied:
    We recommend taking collagen protein for connective tissue health, as it’s high in proline, hydroxyproline, and glycine, and has been proven to improve tendon strength and healing, as well as skin, bone, and gut health. Instead of adding anything, we launched a new whey protein that contains all the essential amino acids, including tryptophan.

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  • Gillian Chesterfield on

    Super interesting. Would you consider adding tryptophan to your collagen powder to round out the aminos? For those of us that can’t tolerate dairy?
    ———
    Chief Nutrition replied:
    Hi Gillian, if you’re avoiding dairy, you can still easily round out the amino acid profile with other whole foods. For example, our collagen bars contain cashews, which naturally provide tryptophan. And of course, our beef bars and biltong are complete proteins in themselves, with all the essential aminos including tryptophan. I’ll add this to the blog for others so thanks for the question!

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